1.
Discuss the three phases of wound healing.
2.
Describe the different groups of growth factors in wound healing.
3.
Discuss the different types of collagen and where they are found.
4.
Tell us about the necessary cofactors of vitamins A & C, zinc and iron.
5.
How does hyperbaric oxygen affect a healing, chronic wound?
Reference(s):
Rohrich, R. (2011). Current concepts in wound healing: update 2011. Plastic and Reconstructive Surgery, 127, 1S-2S.
Fay, A., Nallasamy, N., Bernardini, F., Wladis, E. J., Durand, M. L., Devoto, M. H., … Verity, D. (2015). Multinational Comparison of Prophylactic Antibiotic Use for Eyelid Surgery. JAMA Ophthalmology, 133(7), 778–784.
6.
How is fetal healing different from yours?
Reference(s):
Walmsley, G. G., Maan, Z. N., Wong, V. W., Duscher, D., Hu, M. S., Zielins, E. R., … Longaker, M. T. (2015). Scarless wound healing: chasing the holy grail. Plastic and Reconstructive Surgery, 135(3), 907–917.
7.
Impact of diabetes and hypothyroidism on wound healing.
8.
What effect does nutrition have on healing?
Reference(s):
Kavalukas, S. L., & Barbul, A. (2011). Nutrition and wound healing: an update. Plastic and Reconstructive Surgery, 127 Suppl 1, 38S–43S.
9.
Discuss the effects of smoking on wound healing. Does duration of smoking cessation impact surgical outcomes?
Reference(s):
Rinker, B. (2013). The evils of nicotine: an evidence-based guide to smoking and plastic surgery. Annals of Plastic Surgery, 70(5), 599–605.
Manchio, J. V, Litchfield, C. R., Sati, S., Bryan, D. J., Weinzweig, J., & Vernadakis, A. J. (2009). Duration of smoking cessation and its impact on skin flap survival. Plastic and Reconstructive Surgery, 124(4), 1105–1117.
10.
Would you consider application of growth factors, therapeutic ultrasound and electrical/laser stimulation in promoting wound healing?
Reference(s):
Fan, K., Tang, J., Escandon, J., & Kirsner, R. S. (2011). State of the art in topical wound-healing products. Plastic and Reconstructive Surgery, 127 Suppl 1, 44S–59S.
Rohrich, R. (2011). Current concepts in wound healing: update 2011. Plastic and Reconstructive Surgery, 127, 1S-2S.
11.
Your H&N cancer patient opted for organ preservation treatment of his T3N2a SCCA supraglottis. He now wants you to manage his 4×5 cm neck wound. On exam, it appears superficial, dry and clean, with no signs of healing. How does radiation impact healing?
12.
Educate us on wound care and dressings.
13.
What are your thoughts on peri-operative antibiotics-what and how long?
14.
Tell us about the role of the macrophage and lymphocyte in wound healing.
15.
Tell us about the role of fibronectin, ground substance and collagen. When is the wound strong? Does it ever attain full strength of unwounded skin?
16.
Tell us about the role of myofibroblasts and how contraction takes place.
17.
What does infection do to the wound healing process?
Reference(s):
Gompelman, M., van Asten, S. A., & Peters, E. J. (2016). Update on the Role of Infection and Biofilms in Wound Healing: Pathophysiology and Treatment. Plastic and Reconstructive Surgery, 138(3S):61S-70S.
18.
How are oxygen free radicals generated and what is their role in wound healing?
19.
Educate us on negative pressure wound therapy.
Reference(s):
Orgill, D. P., & Bayer, L. R. (2011). Update on negative-pressure wound therapy. Plastic and Reconstructive Surgery, 127 Suppl 1, 105S–115S.
Webster, J., Scuffham, P., Stankiewicz, M., & Chaboyer, W. P. (2014). Negative pressure wound therapy for skin grafts and surgical wounds healing by primary intention. The Cochrane Database of Systematic Reviews, (10), CD009261.
20.
Discuss the classic principles of wound closure by Halstead.